{"id":10769,"date":"2026-06-09T15:25:22","date_gmt":"2026-06-09T15:25:22","guid":{"rendered":"https:\/\/www.truthforhealth.org\/?p=10769"},"modified":"2026-06-09T15:25:22","modified_gmt":"2026-06-09T15:25:22","slug":"dr-vliets-health-tip-l-ergothioneine-the-longevity-vitamin-that-protects-our-mitochondria-from-everyday-toxins","status":"publish","type":"post","link":"https:\/\/www.truthforhealth.org\/es\/2026\/06\/dr-vliets-health-tip-l-ergothioneine-the-longevity-vitamin-that-protects-our-mitochondria-from-everyday-toxins\/","title":{"rendered":"Dr. Vliet\u2019s Health Tip: L-Ergothioneine: The Longevity Vitamin That Protects Our Mitochondria from Everyday Toxins"},"content":{"rendered":"<p><i><strong>\u00a9 by Elizabeth Lee Vliet MD and Kathy Kresnik<\/strong><\/i><\/p>\n<p>In our modern world, we are constantly exposed to invisible threats \u2014 environmental pollutants, processed foods, stress, UV radiation, and the normal wear-and-tear of daily living. These factors generate oxidative stress that can damage our cells, particularly the mitochondria \u2014 the tiny \u201cpowerhouses\u201d responsible for producing the energy we need to thrive. Then add the COVID shots with spike protein and lipid nanoparticle toxicity and mitochondrial damage to the already long list, and we have a \u201cwitch\u2019s brew\u201d of damaging effects on our body at the cellular level that adds up day in and day out.<\/p>\n<p>What if there was a powerful, naturally occurring compound that could help shield your mitochondria, buffer these everyday toxins, and support healthier aging? Meet <strong>L-Ergothioneine<\/strong> (often simply called ergothioneine, or L-ET), a unique antioxidant amino acid earning the nickname <strong>\u201cThe Longevity Vitamin.\u201d<\/strong><\/p>\n<p>Pioneering researcher Dr. Bruce Ames, known for his groundbreaking work in nutrition and aging, has described ergothioneine as a potential \u201clongevity vitamin\u201d \u2014 because it is the longest lasting, deepest penetrating oral antioxidant that has profound anti-inflammatory actions, eliminates DNA damaging acids, and increases mitochondrial function.<\/p>\n<p><strong>Ergothioneine\u2019s antioxidant capacity is 10 times better than polyphenols found in fruits and vegetables and 34 times more effective than glutathione!\u00a0<\/strong><\/p>\n<p>Based on the exciting research since 2006, ergothioneine is such a powerful nutrient that we now think may be essential not just to prevent deficiency diseases, but also to optimize long-term mitochondrial health and reduce the risk of age-related decline.<\/p>\n<p>I have been recommending <strong>TruMitochondrial\u2122 Boost<\/strong> &#8211; our fermentation-based L-ergothioneine supplement for several years now to help my patients increase cellular energy output and overall energy levels. I feel so strongly about the health benefits of this product that I included it as one of my top supplements in my foundational Resilience Formula. I am even more excited to share with you today exciting <em>additional benefits <\/em>identified in recent research that shows ergothioneine\u2019s protection of cells from the damaging effects of environmental toxins, a <em>cytoprotectant effect added to its other benefits.<\/em><\/p>\n<p><strong>Emerging research shows L-ergothioneine offers impressive benefits:<\/strong><\/p>\n<ul>\n<li><strong>Powerful antioxidant protection against oxidative damage<\/strong><\/li>\n<li><strong>Mitochondrial support \u2014 helping maintain cellular energy production<\/strong><\/li>\n<li><strong>Defense against everyday toxins and inflammatory stressors<\/strong><\/li>\n<li><strong>Potential support for brain health, cardiovascular function, and overall vitality as we age.<\/strong><\/li>\n<\/ul>\n<p>In the sections ahead, I will explore how L-ergothioneine works, the best food sources to naturally boost your levels, practical ways to incorporate it into your daily routine, and why this underappreciated \u201cmushroom miracle\u201d deserves a prominent place in your integrative health strategy.<br \/>\nConsider adding ergothioneine to YOUR daily supplements! Your mitochondria \u2014 and your future health \u2014 will thank you.<\/p>\n<p><strong>What is L-Ergothioneine?<\/strong><\/p>\n<p>L-Ergothioneine (L-ET) is a unique sulfur\u2011containing naturally occurring amino acid derived from histidine which humans must obtain from the diet. It is unique in that it functions more as a vitamin\u2011like antioxidant and cytoprotective micronutrient than a typical amino acid building block.<\/p>\n<p>L-ET is not synthesized by humans or plants but produced by certain fungi and bacteria. <strong><em>Unlike most antioxidants our bodies can make, humans cannot synthesize L-ergothioneine on our own. We must obtain it from our diet \u2014 primarily from certain mushrooms and a few other foods<\/em><\/strong>. Once absorbed, this remarkable compound is selectively transported into tissues under the most oxidative stress, including the brain, heart, lungs, liver, and mitochondria themselves.<\/p>\n<p>In recent years, an abundance of scientific literature has demonstrated L-ET\u2019s antioxidant and cellular protective properties and is driving intense interest in human health applications. L-ET has been shown to\u00a0<a href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0796\/4065\/8242\/files\/TruMitochondrial_Boost.pdf?v=1698795043\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/cdn.shopify.com\/s\/files\/1\/0796\/4065\/8242\/files\/TruMitochondrial_Boost.pdf?v%3D1698795043&amp;source=gmail&amp;ust=1780871349453000&amp;usg=AOvVaw2cYot5UOV_WqdjJIuHQELJ\">decrease the rate of oxidative stress\u2013induced telomere shortening<\/a>, which has implications for human longevity. Clinical studies have shown that L-ET in\u00a0<strong>TruMitochondrial\u2122 Boost<\/strong>\u00a0increased lifespan 12.8% and health span (which is the quality of your lifespan and the more important measure) increased by 42.6%.\u00a0In addition, decreases in nuclear and mitochondrial DNA damage suggest that\u00a0<a href=\"https:\/\/us5.admin.mailchimp.com\/campaigns\/preview-content-html?id=8599086\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/us5.admin.mailchimp.com\/campaigns\/preview-content-html?id%3D8599086&amp;source=gmail&amp;ust=1780871349453000&amp;usg=AOvVaw0WdsNcq-b3WcGkxL5uq7sL\">L-ET is a genomic stabilizer.<\/a>\u00a0In the central nervous system, L-ET\u00a0<a href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0796\/4065\/8242\/files\/TruMitochondrial_Boost.pdf?v=1698795043\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/cdn.shopify.com\/s\/files\/1\/0796\/4065\/8242\/files\/TruMitochondrial_Boost.pdf?v%3D1698795043&amp;source=gmail&amp;ust=1780871349453000&amp;usg=AOvVaw2cYot5UOV_WqdjJIuHQELJ\">crosses the blood\u2013brain barrier and is neuroprotective.<\/a><\/p>\n<p>It is these <strong><em>cellular protective functions <\/em><\/strong>that have really caught my attention, especially in light of the toxic exposure levels we increasingly face every day. Interest in ergothioneine has grown because it appears to protect mitochondria, the energy-producing structures inside cells, from oxidative, nitrosative, and inflammatory damage that can be triggered by chronic exposure to pollutants, industrial chemicals, pesticides, poor air quality, metabolic stress, and aging.<br \/>\nL-ergothioneine does not magically shield every toxin from entering the body, but it helps your cells become more resilient and able to tolerate stress, preserve energy production, protect DNA and membranes, and reduce the inflammatory damage that often follows repeated low-level toxic exposure.<\/p>\n<p><strong>BOTTOM LINE UP FRONT: L-ergothioneine in TruMitochondrial\u2122 Boost helps your cells, particularly our mitochondria, become more resilient and able to tolerate stress and inflammatory damage from toxic exposure.\u00a0 I take it twice a day every day, and consider it my indispensable supplement because of all the benefits I know. <\/strong><\/p>\n<p>In this health tip I discuss why I consider <strong>TruMitochondrial\u2122 Boost<\/strong> as a key component of any protocol designed to support cellular recovery in the areas of healthy aging, occupational exposures, chronic environmental burden, and chronic illness.<\/p>\n<p><strong>Toxic Exposure and the Mitochondria<\/strong><\/p>\n<p>Mitochondria produce most of the usable energy that powers human cells. When mitochondria are damaged, energy production falls, oxidative stress rises, inflammatory signaling intensifies, and tissues with high energy demand such as the brain, heart, muscles, kidneys, liver, and vascular lining become more vulnerable.<\/p>\n<p>Air pollutants, heavy metals, oxysterols, pesticides, solvents, and industrial byproducts can all increase reactive oxygen species, injure mitochondrial membranes and damage mitochondrial DNA. This then impairs energy (ATP) generation and push cells toward chronic dysfunction and poorer health outcomes.<\/p>\n<p><strong>The Active Ingredient in TruMitochondrial\u2122 Boost<\/strong><\/p>\n<p>Ergothioneine must obtained from diet because it is not synthesized by the human body, but the human body has evolved a dedicated transport system to absorb and retain it. This selective uptake indicates to me that ergothioneine serves an important role in protecting cells exposed to ongoing stress. In fact, research has shown that L-ergothioneine is not only actively transported into human tissues it is concentrated in cells under oxidative stress.<\/p>\n<p><strong>L-Ergothioneine gets to the places that need protection most:<\/strong><\/p>\n<p>One of ergothioneine\u2019s most important features is that it is not distributed randomly. <strong><em>Human cells express a specialized transporter known as OCTN1, which actively takes up ergothioneine and concentrates it in tissues that experience high oxidative demand or frequent injury<\/em><\/strong>, including blood cells, liver, kidneys, brain, and other metabolically active tissues. <em>Research also indicates that OCTN1 expression increases in response to oxidative stress,<\/em> meaning stressed tissues may pull in more ergothioneine when they need it most.<\/p>\n<p>This targeted transport matters because many antioxidants look promising in a test tube but fail to reach the intracellular sites where damage actually occurs. Ergothioneine is different because it is actively accumulated by cells and has been shown to enter mitochondria, where it can directly reduce reactive oxygen species and help preserve mitochondrial structure and function.<\/p>\n<p>In other words, this means that <strong>TruMitochondrial Boost is especially helpful not just because it is the strongest antioxidant in the bloodstream, but also because it is delivered to vulnerable cellular compartments where chronic toxic stress does its most important damage<\/strong>.<\/p>\n<p><a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-10767 size-full\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-layzr=\"https:\/\/www.truthforhealth.org\/wp-content\/uploads\/2026\/06\/TruMito.jpg\" alt=\"\" width=\"1024\" height=\"1176\" \/><\/a><\/p>\n<table width=\"100%\">\n<tbody>\n<tr>\n<td>\n<table width=\"100%\">\n<tbody>\n<tr>\n<td>\n<ol>\n<li><strong>Lowering oxidative stress at the mitochondrial level<\/strong><\/li>\n<\/ol>\n<p>A common final pathway for many toxins is oxidative stress. This occurs when cells generate more reactive oxygen species (ROS) then they can safely neutralize, leading to injury of lipids, proteins, enzymes, and DNA.<\/p>\n<p>Ergothioneine is unusually stable at normal pH of human arterial blood because it exists mainly in a <em>thione form<\/em>. This stability allows it to act as an effective scavenger of damaging reactive oxygen and nitrogen species without being rapidly destroyed itself.<\/p>\n<p>In experimental models of toxin-related injury, ergothioneine reduces mitochondrial ROS generation and supports the activity of endogenous detoxification and antioxidant systems. This is important because once mitochondria become oxidatively injured, they often produce even more ROS, <em>creating a self-perpetuating loop of damage. <\/em>Ergothioneine interrupts that destructive loop and helps cells maintain function in the face of repeated low-level exposure to pollutants and chemicals.<\/p>\n<ol>\n<li><strong>Preserving mitochondrial membranes and ATP production<\/strong><\/li>\n<\/ol>\n<p>The mitochondrial membrane is essential for making ATP, the cell\u2019s main energy source. Pollutants, pesticides, oxidized lipids, and industrial chemicals all function to <em>depolarize the membrane<\/em>,<em> increase leakage of electrons, trigger swelling, and impair the respiratory chain producing energy in the cell.<\/em><\/p>\n<p>Research studies show that ergothioneine helps preserve mitochondrial membrane potential, reduce swelling and fragmentation, and support ATP production under stress conditions.<br \/>\nThis is especially important for high-demand tissues such as the heart, brain, skeletal muscle, and vascular endothelium. Cells in these tissues are often the first to show the consequences of mitochondrial decline, including fatigue, poor recovery, vascular dysfunction, and cognitive slowing.<\/p>\n<ol>\n<li><strong>Protecting mitochondrial DNA from cumulative damage<\/strong><\/li>\n<\/ol>\n<p>Mitochondrial DNA sits close to the inner mitochondrial membrane, where reactive oxygen species are generated. Unlike nuclear DNA, it has fewer protective mechanisms and is especially vulnerable to oxidation from chronic toxic exposures.<\/p>\n<p>Ergothioneine has been found to reduce oxidative damage to DNA and to help preserve the integrity of mitochondrial machinery during stress.\u00a0 This is critical because damaged mitochondrial DNA can impair energy production long after the original exposure has passed. Over time, this contributes to a pattern of reduced resilience, poor stress tolerance, and age-related decline that is often seen in chronic illness and repeated environmental burden.<\/p>\n<ol>\n<li><strong>Limiting lipid peroxidation and protein nitration<\/strong><\/li>\n<\/ol>\n<p>Toxic exposures often injure cells by oxidizing membrane lipids and nitrating proteins. These changes can alter membrane fluidity, disable key enzymes, and distort cell signaling. A useful way to think about this is that toxins often do not merely \u201cpoison\u201d the cell once. They can set off chain reactions in fats and proteins that continue damaging the cell long after exposure.<\/p>\n<p><em>Ergothioneine inhibits lipid peroxidation and reduces peroxynitrite-mediated nitration of proteins, two processes that are particularly destructive inside mitochondria. <\/em>Ergothioneine helps slow those damaging chain reactions and preserve the normal function of the cell\u2019s membranes and energy enzymes.<\/p>\n<ol>\n<li><strong>Chelating redox-active metals<\/strong><\/li>\n<\/ol>\n<p>Every day, we\u2019re exposed to pollutants and industrial chemicals that can increase the burden of redox-active metals in our body, such as iron and copper. These metals can trigger a process called the <strong>Fenton reaction<\/strong> \u2014 essentially a chemical reaction that turns normal byproducts of cell metabolism into highly destructive free radicals (like turning a spark into a wildfire).\u00a0 These runaway free radicals damage cell membranes, proteins, mitochondria, and DNA, amplifying injury from environmental exposures.<\/p>\n<p><strong>L-Ergothioneine<\/strong> helps protect against this by binding to these metals and stabilizing them in less reactive forms. This reduces harmful radical production inside cells \u2014 acting like a \u201ccircuit breaker\u201d for oxidative damage.\u00a0 This mechanism is particularly valuable in occupational and environmental medicine. Heavy metals and mixed chemical exposures often cause harm through both <strong>direct toxicity<\/strong> and <strong>secondary oxidative stress<\/strong>. Ergothioneine can help buffer that secondary damage, offering meaningful protection even when the original exposure source cannot be completely eliminated.<\/p>\n<ol>\n<li><strong>Activating the cell\u2019s own defense systems<\/strong><\/li>\n<\/ol>\n<p>Ergothioneine does more than directly quench radicals. It activates Nrf2, a master regulator of antioxidant and detoxification genes. L-ET also increases downstream protective systems involved in glutathione recycling and cellular stress response. As a result, L-ET\u2019s value lies partly in helping cells defend themselves more effectively rather than simply acting as a passive antioxidant.<\/p>\n<p>This distinction is crucial in chronic illness protocols because it is rare that we can succeed in fully <em>\u201cneutralizing all toxins.\u201d<\/em> The long-range goals in chronic illness approaches are to 1) <em>improve resilience, 2) maintain redox balance, and 3) restore normal cellular regulation.\u00a0 <\/em>Together, these three benefits mean the body can better cope with unavoidable stressors in food, water, air, and daily life.<\/p>\n<ol>\n<li><strong>Supporting the MPST-H2S-NAD+ pathway<\/strong><\/li>\n<\/ol>\n<p>Newer research suggests ergothioneine binds to mitochondrial 3-<em>mercaptopyruvate <\/em>sulfurtransferase, or MPST, increasing hydrogen sulfide production and supporting mitochondrial respiration, exercise performance, and NAD+ regeneration. These are exciting directions and important benefits for longevity and energy metabolism.<\/p>\n<p>The practical message is this: Our mitochondria need more than protection from free radicals. They also need efficient signaling, adequate redox balance, and a reliable way to regenerate cofactors such as NAD+ that support energy production. We are learning that <strong><em>ergothioneine actually helps on both sides of that equation by reducing damage and improving mitochondrial efficiency.<\/em><\/strong><\/p>\n<p><strong>Why This Matters for Everyday Life<\/strong><\/p>\n<p>Most people are not exposed to a single dramatic poison. Instead, we all experience a long stream of lower-level stressors: traffic pollution, poor indoor air, microplastics, pesticide residues, wildfire smoke, solvent fumes, industrial runoff, oxidized food compounds, medication burden, chronic inflammation, and the metabolic strain of modern life.<\/p>\n<p>Even when each exposure is modest on its own, the cumulative effect puts an ongoing burden on mitochondria over time, especially in those of us who are older, chronically inflamed, insulin resistant, overtrained, nutrient depleted, or genetically less resilient.<br \/>\nA supplement support strategy based on <strong><em>supporting healthy mitochondrial function <\/em><\/strong>reduces the cellular burden of living in a toxic world. That is why I am so passionate about the way <a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\"><strong>TruMitochondrial\u2122 Boost<\/strong><\/a> works as a daily resilience nutrient to helps our cells incur less damage from unavoidable toxic exposures and recover more effectively from the damage that hits us daily.<\/p>\n<p><strong>An Important Side-note for Occupational Chemical Exposure:<\/strong><\/p>\n<p>Workers in agriculture, manufacturing, construction, transportation, petrochemical settings, salons, cleaning services, healthcare, and industrial facilities commonly face repeated contact with pesticides, solvents, particulates, combustion products, disinfectants, metals, and mixed chemical environments. These exposures have cumulative longterm adverse consequences for mitochondrial function and cellular energy production.\u00a0 Chronic fatigue, feeling sluggish, having low-grade headaches, upper airway irritation, dry coughs, and feeling \u201cfuzzy-brained\u201d are typical symptoms.\u00a0 Other common problems include poor exercise tolerance, slowed recovery from exercise, stress or illness, sleep disturbances, and frequent bouts of illness.<\/p>\n<p>In this context, <a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\"><strong>TruMitochondrial\u2122 Boost<\/strong><\/a> can be a supportive tool rather than a replacement for exposure control. The primary steps in occupational health remain ventilation, protective equipment, exposure reduction, filtration, safe handling, and regulatory compliance. Nutritional support should be viewed as an additional layer that can help improve cellular resilience when exposures cannot be completely avoided.<\/p>\n<p>Ergothioneine clearly has a role in worker-protection strategies aimed at reducing cumulative cellular damage because L-ET is preferentially transported into stressed tissues and protects mitochondrial membranes, DNA, and cellular respiratory function to product energy in the cell. This is especially important for workers with chronic oxidative stress due to repeated inhalational exposure, or combined chemical and metabolic exposures that stress the cellular energy pathways in mitochondria.<\/p>\n<p><strong>Relevance to chronic illness protocols<\/strong><\/p>\n<p>Many chronic illnesses share common mitochondrial damages even when the diagnoses differ. Fatigue syndromes, neuroinflammatory states, vascular dysfunction, metabolic disease, chronic pain, and age-related cognitive decline often involve some combination of oxidative stress, inflammatory signaling, redox imbalance, and impaired energy production all cause similar oxidative damage and impaired mitochondrial function. Ergothioneine\u2019s mechanisms of action at the cellular level fit directly into providing benefits that disrupt the damage.<\/p>\n<p>For these reasons, <a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\"><strong>TruMitochondrial\u2122 Boost<\/strong><\/a> can be a valuable \u201cresilience\u201d supplement for many health problems that share the common denominator of needed mitochondrial support.\u00a0 L-ET supplementation benefits healthy aging, vascular health, neuroprotection, metabolic resilience, and recovery from chronic inflammation.<\/p>\n<p>L-ET is particularly valuable in all these situations because it combines direct mitochondrial protection with regulation of endogenous defense pathways. That means it offers broader benefits than we can get from just a conventional antioxidant that simply circulates briefly in plasma.<\/p>\n<p><strong>A word of CAUTION and BUYER BEWARE CAVEAT:<\/strong> Make sure you chose a top quality L-ET supplement naturally derived from mushrooms.\u00a0 Not all L-ET products are created equally!\u00a0 Some are synthetically made in the lab, rather than natural forms obtained from mushrooms.<\/p>\n<p><strong>TruMitochondrial\u2122 Boost\u00a0is different from other L-ET products in two important ways: <\/strong><\/p>\n<p><strong>(1) Our TruMitochondrial\u2122 Boost\u00a0dose per capsule is higher than other products, so you only need two capsules a day for the 25 mg therapeutic dose clinical studies have shown is the effective dose. <\/strong>\u00a0Other companies typically make 5 mg tabs\/caps, which means you need FIVE a day to get the effective dose, and that drives up the cost quite a lot!<br \/>\n<strong>(2)\u00a0TruMitochondrial\u2122 Boost\u00a0is a 99% pure, concentrated L-ET ingredient derived directly from mushrooms using a proprietary fermentation-based method. <\/strong>This sustainable production method is preferable to chemical synthesis and results in the stable thione-based L-isomer in free amino acid form. Several studies\u00a0<a href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0796\/4065\/8242\/files\/TruMitochondrial_Boost.pdf?v=1698795043\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/cdn.shopify.com\/s\/files\/1\/0796\/4065\/8242\/files\/TruMitochondrial_Boost.pdf?v%3D1698795043&amp;source=gmail&amp;ust=1780871349454000&amp;usg=AOvVaw3BJRNLqBBZdDu7heZvBiHZ\">document the efficacy of ergothioneine<\/a>\u00a0produced via this proprietary method.<\/p>\n<p><strong>TruMitochondrial\u2122 Boost<\/strong><strong>: Benefits Beyond Toxin Buffering<\/strong><\/p>\n<p>In my original health tip <a href=\"https:\/\/www.truthforhealth.org\/es\/2024\/11\/health-tip-from-dr-vliet-trumitochondrial-boost\/\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/www.truthforhealth.org\/2024\/11\/health-tip-from-dr-vliet-trumitochondrial-boost\/&amp;source=gmail&amp;ust=1780871349454000&amp;usg=AOvVaw1ejkpcOyR2JvCJoT2wJ_Rl\">TruMitochondrial\u2122Boost<\/a> we discussed L-ET in terms of longevity and energy levels. We know that blood levels of L-ET decline with age, and a\u00a0faster decline is observed in individuals with mild cognitive impairment.<\/p>\n<p>Cognitive decline and neurodegenerative disease risk is correlated with lower blood ergothioneine levels. The results of a cross-sectional study suggested that serum\u00a0<a href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0796\/4065\/8242\/files\/TruMitochondrial_Boost.pdf?v=1698795043\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/cdn.shopify.com\/s\/files\/1\/0796\/4065\/8242\/files\/TruMitochondrial_Boost.pdf?v%3D1698795043&amp;source=gmail&amp;ust=1780871349454000&amp;usg=AOvVaw3BJRNLqBBZdDu7heZvBiHZ\">L-ET level could be a potential biomarker associated with cognitive impairment.<\/a><\/p>\n<p>Research shows that <strong><em>higher plasma ergothioneine levels<\/em><\/strong> are associated with lower mortality, lower cardiovascular and neurologic disease risk, and less cognitive decline.<\/p>\n<p>In other areas, preclinical and early translational research suggests benefits in vascular health, neuroprotection, exercise endurance, metabolic regulation, and healthy aging. There is emerging data showing benefits on joint comfort and mobility.<\/p>\n<p>Together, all of these exciting research studies explain increasing interest in and support of ergothioneine as a foundational support nutrient rather than a niche antioxidant.<\/p>\n<p><strong>BOTTOM LINE: <a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\">TruMitochondrial\u2122 Boost.<\/a>\u00a0 <\/strong>is not a detox cure, not a substitute for removing exposure sources, and not a guaranteed prevention tool for chronic disease. The existing research does, however, strongly\u00a0 support its role in cellular protection, mitochondrial resilience, and helping us in the goal of healthy aging.<\/p>\n<p>The strength of L-ergothioneine lies in its convergence of mechanisms\u2014let\u2019s review those I have discussed today:\u00a0 1) It is actively transported into stressed tissues, 2) it reaches mitochondria, 3) it reduces oxidative and nitrosamine damage, 4) it modulates inflammatory signaling, 5) it supports endogenous antioxidant pathways, and 6) it improves mitochondrial respiration and NAD+ handling. <strong>Few compounds bring all of those features together in one molecule, so that\u2019s why I am so excited about recommending our <a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\">TruMitochondrial\u2122 Boost<\/a>.\u00a0 <\/strong><\/p>\n<p>If you are concerned about everyday toxic burden just as I am, then I recommend the addition of <a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\"><strong>TruMitochondrial\u2122 Boost<\/strong><\/a> to help your body tolerate modern life better by protecting mitochondria from cumulative wear and tear. This is especially relevant for those living in polluted environments, working around chemicals, recovering from long-term inflammatory stress, or trying to preserve brain, vascular, and metabolic health as we age. Combined with other healthy lifestyle strategies including better nutrition, sleep, exercise, and metabolic health, <a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\"><strong>TruMitochondrial\u2122 Boost<\/strong><\/a> doesn\u2019t alter the need to reduce toxic exposure, but it does help cells stay more resilient in a world where complete avoidance is often impossible.<\/p>\n<p>As I said at the beginning, and often mention in our programs, adding <strong><a href=\"https:\/\/shoptruthforhealth.com\/products\/trumitochondrial-boost?variant=47061555282242\">TruMitochondrial\u2122 Boost<\/a> <\/strong>made a huge different for me personally, and I don\u2019t miss a day taking one in the morning and one at night!\u00a0 Remember, All Truth for Health Foundation Products Meet or Exceed cGMP Quality Standards, the highest quality standard for supplements sold in the USA. <strong><em>For more information, references from studies are listed in the Product Data Sheets for each product, available on our website.<\/em><\/strong>\u00a0 Check us out at <a href=\"http:\/\/www.TruthforHealth.org\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=http:\/\/www.TruthforHealth.org&amp;source=gmail&amp;ust=1780871349454000&amp;usg=AOvVaw3pcjVSKRDlium4TukIezlG\">www.TruthforHealth.org<\/a> Click on tab for Store.\u00a0 OR <a href=\"http:\/\/www.shopTruthforHealth.com\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=http:\/\/www.shopTruthforHealth.com&amp;source=gmail&amp;ust=1780871349454000&amp;usg=AOvVaw06dcTqZlN_IXU_xsGcw8LC\">www.shopTruthforHealth.com<\/a><\/p>\n<p>As you put all the pieces together that I have described today, I encourage you to consider our other natural medicines with our top quality, cGMP-compliant professional formulas:<strong><em> TruNAC\u2122, Tru BioD3, Tru B\u2122 Complex Full Spectrum, TruZinc\u2122, TruC with BioFlavonoids\u00a0 <\/em>(Natural sourced Vitamin<em> C with complete Bioflavonoids), and TruProBiotic\u2122 Daily <\/em><\/strong>to replenish critical bifidobacteria depleted by COVID shots, viral illnesses, and antibiotic therapy.<\/p>\n<p><strong>CAUTION:<\/strong> As always, we urge you to avoid supplements without checking knowledgeable sources to evaluate your medical situation, proper lab tests to verify what is needed, and to make sure to avoid adverse interactions with prescription medicines and other supplements you take.\u00a0 Under medical practice regulations, we are unable to answer individual medical questions or make specific individual supplement recommendations for people who are not established patients of Dr. Vliet\u2019s independent medical practice (<a href=\"http:\/\/www.ViveLifeCenter.com\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=http:\/\/www.ViveLifeCenter.com&amp;source=gmail&amp;ust=1780871349454000&amp;usg=AOvVaw0ydhantayhqa-CB5Mr9Hjo\">www.ViveLifeCenter.com<\/a>).<\/p>\n<p><strong>To Your good health and improving resilience!<\/strong><br \/>\n<strong>Elizabeth Lee Vliet, MD<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table width=\"100%\">\n<tbody>\n<tr>\n<td>\n<table width=\"100%\">\n<tbody>\n<tr>\n<td><a href=\"https:\/\/www.truthforhealth.org\/es\/category\/health-tips\/\"><u><strong>C<\/strong><em><strong>lick here to read Dr. Vliet\u2019s Health Tips<br \/>\non these and more products.<\/strong><\/em><\/u><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"excerpt":{"rendered":"<p>\u00a9 by Elizabeth Lee Vliet MD and Kathy Kresnik In our modern world, we are constantly exposed to invisible threats \u2014 environmental pollutants, processed foods, stress, UV radiation, and the &hellip; <\/p>","protected":false},"author":21,"featured_media":10770,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[222],"tags":[],"class_list":["post-10769","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-tips","fadeIn","image-hover-transition-effect","latest_post"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dr. Vliet\u2019s Health Tip: L-Ergothioneine: The Longevity Vitamin That Protects Our Mitochondria from Everyday Toxins - Truth for Health Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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